Tuesday, 27th February CD1-MR1 2024

•  Virus-driven MAIT activation in vivo - Paul Klenerman
• A protective role for MAIT cells during lung bacterial infections - Christophe Paget
• MR1-dependent activation of MAIT cells by liver-stage malaria parasites - Phoebe M Dewar
• MAIT cells regulate lung inflammation during severe viral pneumonia. - Youenn Jouan
• MAIT cell activation and recruitment drives inflammation and tissue damage in acute appendicitis - Yichao Zheng
• MAIT cells monitor intestinal dysbiosis enabling host protection during colitis - Mariela Fürstenheim Milerud

• MR1Ts Across the Spectrum of Infection with Mtb - David Lewinsohn
• Tissue dependent specialization of human MAIT cells - Johan Sandberg
• BCG vaccination at birth shapes the TCR usage and functional profile of MR1T cells at 9 weeks (#240) - Deborah Lewinsohn
• Development of a novel assay to evaluate MAIT cell secretomes inhibition of carbapenemase activity in carbapenemase-producing Escherichia coli (#242) - Fei Han
• Human unconventional T cells shape the early immune response against Group A Streptococcus (#241) - Christopher Menne
• Rapid but short-lived MR1 presentation of bacterial antigens is sufficient for MAIT cell effector responses (#243) - Xiaoyue Zhang
• Novel MAIT cell-intestinal organoid coculture system to explore the mechanisms of circulating MAIT cell migration into gastrointestinal tissues during acute inflammation (#248) - Zhengyu Wu
• MAIT cells contribute to disease severity in a model of spontaneous colitis. (#231) - LIYEN LOH
• CD1d-restricted unconventional T cells are associated with Crohn’s disease (#232) - Valeriia V Kriukova
• Group A Streptococcus-induced CD1a-autoreactivity contributes to psoriasis (#233) - Yi-Ling Chen

• Title Not Available - Jose Villadangos
• MR1 presents bile acid metabolites as a homeostatic ligand for MAIT cells - Emi Ito
• Adaptive MR1T cells recognise self-metabolites - Andrew Chancellor

1:35 PM - 1:40 PM - Awards

• Modelling MAIT cell tissue homing to the gut using human intestinal organoids - Edwin Leeansyah
• Immune system-microbe crosstalk is mediated by macrophage MR1 antigen presentation. - Hamish EG McWilliam
• The role of CD1a in the initiation of atopic dermatitis-like inflammation using an innate murine model - Karmella Naidoo

• Activation and function of MAIT cells in autoimmune, metabolic and infectious diseases - Agnes Lehuen